This study examined the relationship between religious coping and quality of life in a high school student in Zahedan. The research method is descriptive - correlation. The population is high school male students in Zahedan the 91-92 academic years. In this study, sampling is stratified sampling and using infinite population formula size of 365 subjects selected. Data collected from questionnaires to evaluate quality of life (World Health Organization, 1998) and religiosity questionnaire (Khodayari Fard, 1388) used. Content validity and reliability using Cronbach's alpha coefficient 0.90 for questionnaire to evaluate quality of life and 0.85 for questionnaire to evaluate religiosity obtained. To analysis the questions one-sample t-test, ANOVA and Pearson correlation coefficient used. Single sample t-test results showed that the religious status and the status of the quality of life of students are as much as desired. The results of Pearson correlation coefficient showed that between deal religious with quality of life of students there is a relationship. The ANOVA test results evaluate the religious status of students’ base on education and field of study, there was no difference. According to today's complex and changing world on the one hand, and spiritual and mental pressure at any given moment on the other hand exist in this space. Human beings want to achieve a high level of quality of life in the shadow of the advanced technology of the rapid developments that could achieve it. Human is able to pass in change wave and have the highest possible productivity just with the help of tools that the creator of the universe have put for humans. So on this basis human has no choice but to go to the Lord. Because of research and previous research carried out on the role of religion and religious coping in the quality of life and even human maker knows the remedy.