Autism is a developmental disorder that is characterized by abnormal communicative behaviors, along with restricted interests and repetitive behaviors. Symptoms of this disorder appear before the age of three and its main reason has not been known yet. Prevalence of this disorder is triple among men compare to women, it has a long course, and poor prognosis. This study aims to investigate the impact of Xbox and Kinect game consoles on weight changes and cognitive changes in autistic children. It was a semi-experimental research and was done with pre-test and post-test in two experimental and control groups. Subjects included 30 autistic children chosen randomly and by convenience sampling. Tools for data collection were measurement scales and CPT test. In order to analyze the data, the Wilcoxon test and analysis of covariance and t-test were used. The results showed that the Xbox and Kinect game console affect on weight loss and increased attention of autistic children. Xbox and Kinect game consoles affect on reducing the reaction time of autistic children.