Women in the developing countries are considered the prime hope for promotion of families and growth and development of their countries. Success of entrepreneur women in these communities not only leads to economic benefit but also provides social and cultural benefits. The present research aims to study the role of psychological factors on entrepreneurship and financial independence of entrepreneur women of Mazandaran Province. Research method is of library and field type. Statistical population consists of 1000 entrepreneur women holding a technical and vocational skills certificate in different fields. Then, upon collecting the questionnaire containing 48 questions and analyzing the said questions, research hypotheses were tested. Findings have revealed that there is a direct and indirect meaningful relationship between all tangible variables of learning spirit, inner control, independence at work, risk-taking, creativity, innovation, determination and perseverance and intangible variable of entrepreneurship and financial independence of women. Moreover, all variables of learning spirit, inner control, work independence, risk-taking, creativity, innovation, determination and perseverance on entrepreneurship and financial independence of women of Mazandaran Province. Finally, it has concluded about what subjects involved authorities and managers should be more concerned for more development of the said Province.